What is Wharton’s Jelly?
Wharton’s Jelly is described as a gelatinous substance that can be found within the umbilical cord, the vitreous humor of the eyeball, and made up of hyaluronic acid and chondroitin sulfate. Regenerative medicine is now focusing on the study of mesenchymal stem cells, and the enhanced characteristics that are shown by MSCs is seen as a good and positive change for regenerative medical applications.
Wharton’s Jelly MSCs taken from the human umbilical cord matrix is becoming much more common. The cells in Wharton’s Jelly express several stem cells including that of telomerase. They can now be extracted, cultured and induced to differentiate into mature cells types like neurons. This means that Wharton’s Jelly is now a potential source of adult stem cells. In recent studies, they have shown that Wharton’s Jelly tissue transplantation is able to reduce traumatic brain injury and have great therapeutic potential.
(c) Processing slices of Umbilical Cord to harvest Wharton’s Jelly; CTIBiotech
Wharton’s Jelly Clinical Application:
One of the primary application of Wharton’s Jelly is for tissue engineering. It focuses on stem cells, biomaterials and growth factors. This means that the components of Wharton’s Jelly can be used to regrow and repair damaged tissues that normally do not have the ability to regenerate on their own. Obtaining Mesenchymal stem cells is no longer ethically controversial which makes it an ideal source for medical researchers and clinics. Human Wharton’s Jelly cells are highly desirable due to their abundance in supply.
Stem Cell Clinics are now collecting life-saving Wharton’s Jelly-derived mesenchymal stem cells. There is now strong evidence that these cells contain therapeutic properties. Collecting a person’s Wharton’s Jelly MSC is relatively safe and devoid of side effects making them ideal for regenerative medicine applications. It can be used for direct replacement of injured tissue cells, it can also protect tissue from stress-induced apoptosis, and protect the body from inflammation.
Wharton’s Jelly, Human Aging, and cure for Diabetes Mellitus:
As humans age, we experience cell death, senescence, or loss of regenerative function and in extreme cases neoplastic transformation. As we get older, the ability of the body to heal and repair itself decreases making us susceptible to a range of diseases. Obesity and Diabetes also lead to the reduction of healthy cells in the body, leading to a range of diseases and unwanted occurrences in the body. For this reason, there are now a lot of clinical trials that are testing the use of Wharton’s Jelly MSC through intravenous delivery. A control group of patients with Diabetes Mellitus are given the daily dosage of WJ-MSC treatment and so far 3 out of 15 patients usually recover and stop their use and need of insulin. ( https://www.hindawi.com/journals/bmri/2015/430847/). Patients with Diabetes 1 Mellitus and Diabetes 2 Mellitus have exhibited immense recovery and results after application of Wharton’s Jelly.
With the right use and clinical implication of oxidative stress, telomere length and procedure disease can be impaired even with aged patients. Aging patients now have the option of stem cells treatments. Wharton’s Jelly Mesenchymal offers high efficiency for recovery. Stem cell clinics like Feeling Good At Any Age The One-Stop Rejuvenation Clinic in California is deep in their research when it comes to clinical applications. They offer well managed and qualified management systems when it comes to providing quality care, testing, and distribution of stem cells.
Today Wharton’s Jelly MSC can be applied safely and immediately, allowing so many astounding medical breakthroughs.
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- Wharton’s jelly in the Merriam-Webster Medical Dictionary.
- Mitchell KE, Weiss ML, Mitchell BM, Martin P, Davis D, Morales L, Helwig B, Beerenstrauch M, Abou-Easa K, Hildreth T, Troyer D, Medicetty S. Matrix cells from Wharton’s jelly form neurons and glia. Stem Cells. 2003;21(1):50-60.